Product Datasheet  
DP-1 Antibody  
Catalog Number: 21654  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q14186
    NCBI Protein: NP_009042.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.13~17(E-L-K-V-F) derived from Human DP-1
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Predicted MW: 45kd
    Western blotting: 1:500~1:1000
     

  • other_names：  
  • Dp-1; TFDP1; DRTF1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous levels of total DP-1 protein.
  • Applications：  
  • WB
  • Background：  

  • Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.

    Wu C.-L., Zukerberg L.R., Ngwu C., Harlow E., Lees J.A.Mol. Cell. Biol. 15:2536-2546(1995)




 
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