Product Datasheet
Rab5 Antibody
Catalog Number: 21628
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P20339
NCBI Protein: NP_004153.2
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.188~192( N-P-G-A-N) derived from Human Rab5.
- appl_detail:
- Predicted MW: 25kd
Western blotting: 1:500~1:1000
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous level of total Rab5 protein.
- Background:
- Required for the fusion of plasma membranes and early endosomes.
Callaghan J.M., Nixon S., Bucci C., Toh B.-H., Stenmark H.Eur. J. Biochem. 265:361-366(1999) Hoffenberg S., Liu X., Nikolova L., Hall H.S., Dai W., Baughn R.E., Dickey B.F., Barbieri M.A., Aballay A., Stahl P.D., Knoll B.J.J. Biol. Chem. 275:24661-24669(2000)
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