Product Datasheet  
GluR1 Antibody  
Catalog Number: 21575  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P42261
    NCBI Protein: NP_000818.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa. 831~835 (K-S-R-S-E) derived from Human GluR1
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 110kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • GLR1; GLUH1; GRIA1; GluR-1; GluR-A
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous levels of total GluR1 protein.
  • Applications：  
  • WB
  • Background：  
  • Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Emamian ES, et al. (2004) J Neurosci. 24(7): 1561-4
    Palmer, C.L. et al. (2005) Pharmacol. Rev. 57, 253-277.



 
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