Product Datasheet  
Glutamine Synthetase Antibody  
Catalog Number: 21650  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15104
    NCBI Protein: NP_001028216.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.365~369(G-D-E-P-F) derived from Human Glutamine Synthetase
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 42kd
    Western blotting: 1:500~1:1000
     

  • other_names：  
  • GS; GLNS; PIG43; PIG59;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous levels of total Glutamine Synthetase protein.
  • Applications：  
  • WB
  • Background：  

  • This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner . Essential for proliferation of fetal skin fibroblasts. "Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase."
    Boksha I.S., Schonfeld H.J., Langen H. Biokhimiia 67:1012-1020(2002) "Glutamine synthetase is essential for proliferation of fetal skin fibroblasts."
    Vermeulen T., Goerg B., Vogl T. Arch. Biochem. Biophys. 478:96-102(2008)




 
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