Product Datasheet  
cofilin1/cofilin2(Ab-88) Antibody  
Catalog Number: 21507  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P23528
    Gene ID:1072
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa. 86~90 (A-T-Y-E-T) derived from Human cofilin1/cofilin2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 19kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:200

  • other_names：  
  • Cofilin; non-muscle isoform 18 kDa phosphoprotein;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total cofilin1/cofilin2 protein.
  • Applications：  
  • WB IHC IF
  • Background：  

  • Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

    Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830.
    Arber, S. et al. (1998) Nature 393, 805-809.
    Yang, N. et al. (1998) Nature 393, 809-812.




 
© Signalway Biotechnology All Rights Reserved.