Product Datasheet  
CD10 Antibody  
Catalog Number: 21490  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P08473
    NCBI Protein: NP_000893.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.6~10(S-Q-M-D-I) derived from Human CD10.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 100kd
    Western blotting: 1:500
  • other_names：  
  • NEP; MME; SFE; CALLA; MGC126681
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total CD10 protein.
  • Applications：  
  • WB
  • Background：  
  • Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

    Yandle T.G., Brennan S.O., Espiner E.A., Nicholls M.G., Richards A.M.Peptides 10:891-894(1989)
    Rice G.I., Thomas D.A., Grant P.J., Turner A.J., Hooper N.M.Biochem. J. 383:45-51(2004)
    Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G.J. Biol. Chem. 285:39819-39827(2010)



 
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