Product Datasheet  
SHP-2(Ab-580) Antibody  
Catalog Number: 21320  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q06124
    NCBI Protein: NP_002825.3
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.578~582 (R-V-Y-E-N) derived from Human SHP-2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 72kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:200
  • other_names：  
  • Protein-tyrosine phosphatase 2C
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total SHP-2 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

    Ferjoux G, et al. (2003) Mol Biol Cell. 2003; 14(9): 3911-3928.
    Shi ZQ, et al. (2000) Mol Cell Biol ; 20(5): 1526-1536.



 
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