Product Datasheet  
Connexin 43(Ab-368) Antibody  
Catalog Number: 21250  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P17302
    NCBI Protein: NP_000156.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa. 366~370 (R-A-S-S-R) derived from Human Connexin 43.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 43kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100

  • other_names：  
  • CX43; CXA1; CXN-43; Connexin 43; GJA1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total Connexin43 protein.
  • Applications：  
  • WB IHC
  • Background：  

  • One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

    Joell L. Solan1, et al. (2003) Cell Science 116: 2203-2211
    Satoshi Matsushita, et al. (2006) Histochemistry and Cytochemistry 54 (3): 343-353,
    Xiaoyong Bao, et al. (2004) Cell Physiol 286: C647-C654
    W. E. I. Li, et al.(1998) European Journal of Neuroscience 10: 2444




 
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