Product Datasheet  
EGFR(Ab-869) Antibody  
Catalog Number: 21222  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P00533
    NCBI Protein: NP_005219.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.867~871 (K-E-Y-H-A) derived from Human EGFR.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 175kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Receptor tyrosine-protein kinase ErbB-1; ERBB1;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total EGFR protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

    Gingras AC, et al. (1998) Genes Dev 12(4): 502-513.
    Brugarolas J, et al. (2004) Genes Dev 18(23): 2893-2904.
    Kumar V, et al. (2000) EMBO J 19(5): 1087-1097.
    Moody CA, et al. (2005) J Virol 79(9): 5499-5506.
    Burnett PE, et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.



 
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