Product Datasheet  
FAK(Ab-397) Antibody  
Catalog Number: 21208  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q05397
    NCBI Protein: NP_005598.3
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa. 395~399 (D-D-Y-A-E) derived from Human FAK.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 125kd
    Western blotting: 1:500~1:1000

  • other_names：  
  • FADK; PTK2; FAK1; FRNK; PTK2
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous levels of total FAK protein.
  • Applications：  
  • WB
  • Background：  

  • Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

    von Sengbusch A, et al. (2005) Am J Pathol ; 166(2): 585-596
    Fornaro M, et al. (2000) Mol Biol Cell ; 11(7): 2235-2249
    Zhang X, et al. (1999) Proc Natl Acad Sci U S A; 96(16): 9021-9026.




 
© Signalway Biotechnology All Rights Reserved.