Product Datasheet  
MyoD(Ab-200) Antibody  
Catalog Number: 21124  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15172
    NCBI Protein: NP _002469.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.198~202 (A-S-S-P-R) derived from Human MyoD.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 40kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • MYF3; MYOD; MYOD1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total MyoD protein.
  • Applications：  
  • WB
  • Background：  
  • MyoD encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

    Emmanuel G, et al. J. Biol. Chem., Jun 2000; 275: 18767 - 18776
    Tintignac LA, et al. Mol Cell Biol. 2004 Feb; 24(4): 1809-1821.
    Kitzmann M, et a. Mol Cell Biol. 1999 Apr; 19(4): 3167-3176.



 
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