Product Datasheet  
Ezrin(Ab-353) Antibody  
Catalog Number: 21094  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15311
    NCBI Protein: NP_001104547.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.351~355 (Q-D-Y-E-E) derived from Human EZRIN.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 81kd
    Western blotting: 1:500~1:1000

  • other_names：  
  • Cytovillin; EZRI; VIL2; Villin 2; p81
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total Ezrin protein.
  • Applications：  
  • WB
  • Background：  

  • Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

    Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25): 9485-90.
    Wang Q, et al. (2003) J Biol Chem 278(48): 47731-43.
    Gautreau A, et al. (1999) Proc Natl Acad Sci U S A: 96(13): 7300-5.
    Crepaldi T, et al. (1997) J Cell Biol: 28; 138(2): 423-34.




 
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