Product Datasheet  
EGFR(Ab-1092) Antibody  
Catalog Number: 21074  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P00533
    NCBI Protein: NP_005219.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa. 1090~1094 (P-E-Y-I-N) derived from Human EGFR.
  • reactivity：  
  • Hu Rt
  • appl_detail：  
  • Predicted MW: 175kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • Receptor tyrosine-protein kinase ErbB-1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total EGFR protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

    Buerger C, et al. (2003) J Biol Chem; 278(39): 37610-21.
    Wang XQ, (2003) J Biol Chem; 278(49): 48770-8.
    Saito T, et al. (2004) Endocrinology; 145(9): 4232-43.
    Pao W, et al. (2004) Proc Natl Acad Sci U S A; 101(36): 13306-11.
    Mattila E, et al. (2005) Nat Cell Biol; 7(1): 78-85.



 
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