Product Datasheet  
STAT3(Ab-705) Antibody  
Catalog Number: 21045  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P40763
    NCBI Protein: NP_003141.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around aa.703~707(A-P-Y-L-K) derived from Human STAT3.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 88kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: IF:1:100~1:200
  • other_names：  
  • APRF; Acute-phase response factor; HIES
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total STAT3 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

    Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120.
    Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804.
    Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115.
    Garcia R, et al. (1998) J Biomed Sci. 5: 79-85.
    Bromberg J F, et al. (1999) Cell. 98: 295-303.




 
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