Product Datasheet
PRLR Antibody
Catalog Number: 21457
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P16471
NCBI Protein: NP_000940.1
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Immunogen:
- Peptide sequence around aa.25~29 (Q-L-P-P-G) derived from Human PRLR
- appl_detail:
- Predicted MW: 70kd
Western blotting: 1:500~1:1000
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Specificity:
- The antibody detects endogenous levels of total PRLR protein.
- Background:
- This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling
Boutin J.M,et al.Mol. Endocrinol. 3:1455-1461(1989)
Kline J.B,et al.J. Biol. Chem. 274:35461-35468(1999)
Hu Z.Z,et al.J. Clin. Endocrinol. Metab. 84:1153-1156(1999)
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