Product Datasheet  
TRPC6 Antibody  
Catalog Number: 21403  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q61143
    NCBI Protein: NP_004612.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • peptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 100kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • TRP6; FSGS2; FLJ11098
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

    Koichiro Kuwahara et al. (2006) J Clin Invest. 116(12): 3114



 
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