Product Datasheet
Myb (Phospho-Ser532) Antibody
Catalog Number: 12145
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P10242;
NCBI Gene#:4602
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Peptide sequence around phosphorylation site of serine 532 (V-E-S(p)-P-T) derived from Human Myb.
- appl_detail:
- Immunohistochemistry: 1:50~1:100
- other_names:
- C-myb; Myb proto-oncogene protein
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous levels of Myb only when phosphorylated at serine 532.
- Background:
- Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
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