Product Datasheet
BIK (Phospho-Thr33) Antibody
Catalog Number: 12131
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13323;
NCBI Gene#:638
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 33 (G-M-T(p)-D-S) derived from Human BIK.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- Apoptosis inducer NBK; BIKLK; BIP1; BP4; Bcl-2 interacting killer; NBK
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous levels of BIK only when phosphorylated at threonine 33.
- Background:
- Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
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