Product Datasheet  
BIK (Phospho-Thr33) Antibody  
Catalog Number: 12131  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q13323;
    NCBI Gene#:638
  • Form of Antibody:  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Peptide sequence around phosphorylation site of threonine 33 (G-M-T(p)-D-S) derived from Human BIK.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names:  
  • Apoptosis inducer NBK; BIKLK; BIP1; BP4; Bcl-2 interacting killer; NBK
  • Purification:  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity:  
  • The antibody detects endogenous levels of BIK only when phosphorylated at threonine 33.
  • Applications:  
  • WB IHC
  • Background:  
  • Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.



 
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