Product Datasheet  
Histone H3(Phospho-Thr11) Rabbit Polyclonal Antibody  
Catalog Number: 12085  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P68431
  • Form of Antibody：  
  • PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Peptide sequence around phosphorylation site of threonine 11(K-S-T(p)-G-G) derived from Human Histone H3.
  • reactivity：  
  • Hu Rt Ms
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • H3 histone antibody; HIST1H3A antibody; Histone cluster 1; H3a antibody
  • Purification：  
  • Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Specificity：  
  • The Histone H3(Phospho Thr11) Rabbit Polyclonal Antibody detects endogenous Histone H3(Phospho Thr11) protein.
  • Applications：  
  • WB
  • Background：  
  • Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.



 
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