Product Datasheet  
Smad1 (Phospho-Ser187) Antibody  
Catalog Number: 12074  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q15797;
    NCBI Gene#: 4086;
    NCBI Protein#: NP_001003688.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 187 (P-H-S(p)-P-N) derived from Human Smad1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 55,60kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • BSP1, JV41, BSP-1, JV4-1, MADH1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of Smad1 only when phosphorylated at Serine 187.
  • Applications：  
  • WB
  • Background：  
  • Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.



 
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