Product Datasheet  
AhR (Phospho-Ser36) Antibody  
Catalog Number: 12072  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P35869/A9YTQ3;
    NCBI Gene#: 196/57491;
    NCBI Protein#: NP_001612.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 36 (N-P-S(p)-K-R) derived from Human AhR.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 90kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • bHLHe76
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of AhR only when phosphorylated at Serine 36.
  • Applications：  
  • WB
  • Background：  
  • Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.



 
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