Product Datasheet  
B-RAF (Phospho-Ser446) Antibody  
Catalog Number: 12064  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P15056;
    NCBI Gene#: 673;
    NCBI Protein#: NP_004324.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 446 (R-D-S(p)-S-D) derived from Human B-RAF.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 110kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • NS7, BRAF1, RAFB1, B-RAF1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of B-RAF only when phosphorylated at Serine 446.
  • Applications：  
  • WB
  • Background：  
  • Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.



 
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