Product Datasheet  
IL-8R beta/CDw128 beta (Phospho-Ser347) Antibody  
Catalog Number: 12051  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P25025;
    NCBI Gene#: 3579;
    NCBI Protein#: NP_001161770.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 347 (R-P-S(p)-F-V) derived from Human IL-8R beta/CDw128 beta
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 48kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • CD182, IL8R2, IL8RA, IL8RB, CMKAR2
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of IL-8R beta/CDw128 beta only when phosphorylated at Serine 347.
  • Applications：  
  • WB
  • Background：  
  • Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.



 
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