Product Datasheet
GATA4 (Phospho-Ser105) Antibody
Catalog Number: 12044
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P43694;
NCBI Gene#: 2626;
NCBI Protein#: NP_002043.2
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 105
(P-V-S(p)-P-R) derived from Human GATA4.
- appl_detail:
- Predicted MW: 44kd
Western blotting: 1:500~1:1000
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous level of GATA4 only when phosphorylated at Serine 105.
- Background:
- Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement.
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