Product Datasheet
Keratin 8 (Phospho-Ser432) Antibody
Catalog Number: 12042
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P05787;
NCBI Gene#: 3856;
NCBI Protein#: NP_001243211.1
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 432
(L-T-S(p)-P-G) derived from Human Keratin 8.
- appl_detail:
- Predicted MW: 53kd
Western blotting: 1:500~1:1000
- other_names:
- K8, KO, CK8, CYK8, CK-8
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous level of Keratin 8 only when phosphorylated at Serine 432.
- Background:
- Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
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