Product Datasheet  
PPAR-BP (Phospho-Thr1457) Antibody  
Catalog Number: 12023  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q15648;
    NCBI Gene#: 5469;
    NCBI Protein#: XP_005257523.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Threonine 1457 (A-Y-T(p)-P-Q) derived from Human PPAR-BP.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 168kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • PBP, CRSP1, RB18A, TRIP2, PPARBP
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of PPAR-BP only when phosphorylated at Threonine 1457.
  • Applications：  
  • WB
  • Background：  
  • Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.



 
© Signalway Biotechnology All Rights Reserved.