Product Datasheet
HSL (Phospho-Ser552) Antibody
Catalog Number: 12010
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q05469;
NCBI Gene#: 3991;
NCBI Protein#: NP_005348.2
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of serine 552
(V-L-S(p)-S-L) derived from Human HSL.
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous level of HSL only when phosphorylated at Serine 552.
- Background:
In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.
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