Product Datasheet  
Estrogen Receptor- beta (Phospho-Ser105) Antibody  
Catalog Number: 11998  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q92731;
    NCBI Gene#: 2100;
    NCBI Protein#: NP_001035365.1
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine105(Q-R-S(p)-P-W) derived from Human Estrogen Receptor- beta.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • ESR2; ESTRB; Estrogen receptor beta; NR3A2;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of Estrogen Receptor- beta only when phosphorylated at serine 105.
  • Applications：  
  • WB
  • Background：  

  • Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

    Hamilton-Burke W, et al. (2010)Am J Pathol 177, 1079-86. St-Laurent V, Sanchez M, Charbonneau C, Tremblay A (2005) J Steroid Biochem Mol Biol 94, 23-37. Tremblay A, Tremblay GB, Labrie F, Gigu¨¨re V (1999) Mol Cell 3, 513-9 .




 
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