Product Datasheet  
Calmodulin (Phospho-Thr79/Ser81) Antibody  
Catalog Number: 11978  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P62158;
    NCBI Gene#: 808;
    NCBI Protein#: NP_005175.2
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of threonine79/serine81(K-D-T(p)-D-S(p)-E-E) derived from Human Calmodulin .
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • CALM; CALM1; CALM2; CALM3; CAM
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of Calmodulin only when phosphorylated at threonine 79/serine 81.
  • Applications：  
  • WB
  • Background：  

  • Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.

    Allen D, Fakler B, Maylie J, Adelman JP (2007) J Neurosci 27, 2369-76
    Arrigoni G, et al. (2004) Biochemistry 43, 12788-98
    Greif DM, Sacks DB, Michel T (2004) Proc Natl Acad Sci U S A 101, 1165-70




 
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