Product Datasheet  
STAT5A/B (Phospho-Ser725/730) Antibody  
Catalog Number: 11977  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P42230/P42232;
    NCBI Gene#: 20850/20851;
    NCBI Protein#: NP_001275647.1/NP_036580.2
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine725/730(A-P-S(p)-P-V) derived from Human STAT5A/B.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • Signal transducer and activator of transcription 5B; STA5B; STAT5; transcription factor STAT5B;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of STAT5A/B only when phosphorylated at serine 725/ serine 730.
  • Applications：  
  • WB
  • Background：  

  • Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.

    Ross JA, et al. (2010) J Biol Chem 285, 3582-91
    Uddin S, et al. (2003) Biochem Biophys Res Commun 308, 325-30
    Xue HH, et al. (2002) Int Immunol 14, 1263-71




 
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