Product Datasheet  
n-NOS (Phospho-Ser852) Antibody  
Catalog Number: 11975  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P29475;
    NCBI Gene#: 4842;
    NCBI Protein#: NP_000611.1
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine 852(F-N-S(p)-V-S) derived from Human n-NOS .
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • bNOS; Constitutive NOS; IHPS1; N-NOS; NC-NOS
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of n-NOS only when phosphorylated at serine 852.
  • Applications：  
  • WB
  • Background：  

  • Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

    Capettini LS, et al. (2011) DBr J Pharmacol 164, 1738-48
    Ferreira JM, Burnett AL, Rameau GA (2011) J Neurosci 31, 1991-9
    Chaudhury A, Rao YM, Goyal RK (2008) Am J Physiol Gastrointest Liver Physiol 295, G442-51




 
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