Product Datasheet  
14-3-3 zeta/ delta (Phospho-Thr232) Antibody  
Catalog Number: 11954  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P63104;
    NCBI Gene#: 7534;
    NCBI Protein#: NP_001129171.1
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of threonine232(S-D-T(p)-Q-G) derived from Human 14-3-3 zeta/ delta .
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • 1433Z; 143Z; FAS; YWHAZ;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of 14-3-3 zeta/ delta only when phosphorylated at threonine 232.
  • Applications：  
  • WB
  • Background：  

  • Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

    Sluchanko NN, et al. (2011) Arch Biochem Biophys 506, 24-34
    Sluchanko NN, et al. (2008) Arch Biochem Biophys 477, 305-12
    Clokie SJ, et al. (2005) FEBS J 272, 3767-76




 
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