Product Datasheet  
Kv2.1 (Phospho-Ser805) Antibody  
Catalog Number: 11923  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q14721;
    NCBI Gene#: 2745;
    NCBI Protein#: NP_004966.1
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine805(P-T-S(p)-P-K) derived from Human Kv2.1 .
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:1000
  • other_names：  
  • DRK1; KCB1; KCNB1; Potassium channel Kv2.1; Potassium voltage-gated channel subfamily B member 1
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of Kv2.1 only when phosphorylated at serine 805.
  • Applications：  
  • WB
  • Background：  

  • Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.

    McCord MC, Aizenman E (2013)Proc Natl Acad Sci U S A 110, 13988-93 . Norris CA, et al. (2012) J Neurosci 32, 8865-70 . Cerda O, Trimmer JS (2011)J Biol Chem 286, 28738-48 .




 
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