Product Datasheet  
ITGB1 (Phospho-Tyr795) Antibody  
Catalog Number: 11824  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P05556;
    NCBI Gene#: 3688;
    NCBI Protein#: NP_002202.2.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 795(P-K-Y(p)-E-G) derived from Human ITGB1 .
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • CD29; FNRB; ITB1;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of ITGB1 only when phosphorylated at tyrosine 795.
  • Applications：  
  • WB
  • Background：  

  • Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

    Argraves W.S., J. Cell Biol. 105:1183-1190(1987).
    Ota T., Nat. Genet. 36:40-45(2004).
    Bechtel S., BMC Genomics 8:399-399(2007).




 
© Signalway Biotechnology All Rights Reserved.