Product Datasheet  
TAL-1 (Phospho-Ser122) Antibody  
Catalog Number: 11814  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P17542;
    NCBI Gene#: 6886;
    NCBI Protein#: NP_001274276.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • SCL; TAL1; TCL5;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of TAL-1 only when phosphorylated at serine 122.
  • Applications：  
  • WB
  • Background：  

  • TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

    Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).
    Gregory S.G., Nature 441:315-321(2006).
    Chen Q., J. Exp. Med. 172:1403-1408(1990).




 
© Signalway Biotechnology All Rights Reserved.