Product Datasheet  
MEF2C (Phospho-Ser396) Antibody  
Catalog Number: 11808  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q06413;
    NCBI Gene#: 4208;
    NCBI Protein#: NP_001180279.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 396(P-V-S(p)-P-P) derived from Human MEF2C.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100

  • other_names：  
  • Myocyte enhancer factor 2C; Myocyte-specific enhancer factor 2C; Similar to MADS box transcription enhancer factor 2 polypeptide C;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of MEF2C only when phosphorylated at serine 396.
  • Applications：  
  • WB IHC
  • Background：  

  • MEF2C transcription factor of the MADS family which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in myogenesis, neurogenesis and in the development of cortical architecture. Three splice-variant isoforms have been described.

    Leifer D., Proc. Natl. Acad. Sci. U.S.A. 90:1546-1550(1993).
    McDermott J.C., Mol. Cell. Biol. 13:2564-2577(1993).
    Wang A.H., Mol. Cell. Biol. 19:7816-7827(1999).




 
© Signalway Biotechnology All Rights Reserved.