Product Datasheet  
Claudin 6 (Phospho-Tyr219) Antibody  
Catalog Number: 11793  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P56747;
    NCBI Gene#: 9074;
    NCBI Protein#: NP_067018.2.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 219 (T-K-N-Y(p)-V) derived from Human Claudin 6.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • claudin 6; claudin-6; CLD6; Skullin 2;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of Claudin 6 only when phosphorylated at tyrosine 219.
  • Applications：  
  • WB
  • Background：  

  • Claudin 6 Plays a major role in tight junction-specific obliteration of the intercellular space. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO- 3.

    Keen T.J., Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
    Troy T., Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
    Clark H.F., Genome Res. 13:2265-2270(2003).




 
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