Product Datasheet  
VEGFR1 (Phospho-Tyr1048) Antibody  
Catalog Number: 11759  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P17948;
    NCBI Gene#: 2321;
    NCBI Protein#: NP_002010.2.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 1048 (D-I-Y(p)-K-N) derived from Human VEGFR1.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100

  • other_names：  
  • VGFR1; FRT; FLT1; FLT;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of VEGFR1 only when phosphorylated at tyrosine 1048.
  • Applications：  
  • IHC
  • Background：  

  • Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

    Shibuya M., Oncogene 5:519-524(1990).
    Kendall R.L., Proc. Natl. Acad. Sci. U.S.A. 90:10705-10709(1993).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).




 
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