Product Datasheet  
PDK1 (Phospho-Tyr9) Antibody  
Catalog Number: 11719  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O15530;
    NCBI Gene#: 5170;
    NCBI Protein#: NP_002604.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 9(A-L-Y(p)-D-A) derived from Human PDK1.
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:50~1:100

  • other_names：  
  • hPDK1; PDPK1; mPDK1; PkB kinase;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of PDK1 only when phosphorylated at tyrosine 9.
  • Applications：  
  • IHC
  • Background：  

  • Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.

    Alessi D.R., Curr. Biol. 7:261-269(1997).
    Alessi D.R.,Curr. Biol. 7:776-789(1997).
    Stephens L.R.,Science 279:710-714(1998)




 
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