Product Datasheet
c-Jun (Phospho-Ser63) Antibody
Catalog Number: 11710
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P05412;
NCBI Gene#: 3725;
NCBI Protein#: NP_002219.1.
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of Serine 63(L-T-S(p)-P-D) derived from Human c-Jun.
- other_names:
- AH119; c-Jun; p39; Jun A; AP1
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The Antibody detects endogenous levels of c-Jun only when phosphorylated at Serine 63.
- Background:
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
Wei W, et al. (2005). Cancer Cell. 8(1): 25-33.
Sevilla A, et al. (2004). Oncogene.23(55): 8950-8958.
Li L, et al. (2004). J Biol Chem.279(6): 4058-4065.
Hurd C, et al. (2002). Oncogene.21(14): 2154-2160.
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