Product Datasheet  
PKA-R2β (Phospho-Ser114) Antibody  
Catalog Number: 11692  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P31323;
    NCBI Gene#: 5577;
    NCBI Protein#: NP_002727.2.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine114(R-A-S(p)-V-C) derived from Human PKA-R2β.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • KAP3; PRKAR2B; PKA R2-beta;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of PKA-R2β only when phosphorylated at serine 114.
  • Applications：  
  • WB
  • Background：  

  • Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

    Levy F.O., Mol. Endocrinol. 2:1364-1373(1988).
    DeGiorgis J.A., J. Proteome Res. 4:306-315(2005).
    Han G., Proteomics 8:1346-1361(2008)




 
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