Product Datasheet  
CD3 ζ (Phospho-Tyr142) Antibody  
Catalog Number: 11655  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P20963;
    NCBI Gene#: 919;
    NCBI Protein#: NP_000725.1.
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 142 (G-L-Y(p)-Q-G) derived from Human CD3 ζ.
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Western blotting: 1:500~1:1000

  • other_names：  
  • T3Z; CD3-zeta; TCRZ; T-cell receptor T3 zeta chain;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous levels of CD3 ζ only when phosphorylated at tyrosine 142.
  • Applications：  
  • WB
  • Background：  

  • Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.

    Linda A. Trimble, Blood, Aug 2000; 96: 1021 - 1029.
    Sandeep Krishnan, J. Immunol., Sep 2005; 175: 3417 - 3423.
    Linda A. Trimble, J. Virol., Aug 2000; 74: 7320 - 7330.
    Hisashi Arase, J. Immunol., Jan 2001; 166: 21.




 
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