Product Datasheet  
Sufu(Phospho-Ser342) Antibody  
Catalog Number: 11552  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q9UMX1
    NCBI Protein: NP_057253.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of Serine 342 (A-P-S(p)-R-K) derived from Human Sufu.
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 54kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • SUFUH
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
  • Applications：  
  • WB
  • Background：  
  • SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700)

    Zimmern P,et al.(2010) Neurourol Urodyn.29(5):715-8.
    Wang C,et al. (2010) Development. 137(12):2001-9.
    Rabasseda X.et al.(2010) Drug News Perspect.23(4):273-5.



 
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