Product Datasheet  
Her3/ErbB3(phospho-Tyr1328) Antibody  
Catalog Number: 11510  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P21860
    NCBI Protein: NP_001005915.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 1328 (P-D-Y(p)-W-H) derived from Human Her3/ErbB3.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 185kd
    Western blotting: 1:500~1:1000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:200
  • other_names：  
  • Tyrosine kinase-type cell surface receptor HER3
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of Her3/ErbB3 only when phosphorylated at tyrosine 1328.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Binds and is activated by neuregulins and NTAK.

    Holbro, T. et al. (2003) Proc. Natl. Acad. Sci. USA 100, 8933-8938.
    Kobayashi, M. et al. (2003) Oncogene 22, 1294-1301.
    Kim, H.H. et al. (1994) J. Biol. Chem. 269, 24747-24755.
    Yarden, Y. and Sliwkowski, M.X. (2001) Nature Rev. Mol. Cell. Biol. 2, 127-137.



 
© Signalway Biotechnology All Rights Reserved.