Product Datasheet  
WNT3A/WNT3 Antibody  
Catalog Number: 48348  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Goat
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P56703
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:100-1:1,000



  • other_names：  
  • Int 4 antibody
    INT4 antibody
    MGC131950 antibody
    MGC138321 antibody
    MGC138323 antibody
    Proto-oncogene Int-4 homolog antibody
    Proto-oncogene Wnt-3 antibody
    wingless type MMTV integration site family member 3 antibody
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP
  • Background：  
  • The Wnt gene family encodes secreted signaling molecules that bind to frizzled receptors and influence oncogenesis and developmental processes, including regulation of cell fate and patterning during embryogenesis. The Wnt family has two functional classes according to their biological activities; Wnts that signal through a Wnt-1/wingless pathway by stabilizing cytoplasmic β-catenin, and Wnts that stimulate intracellular Ca2+ release and activate two kinases, CamKII and PKC, in a G protein-dependent manner. Wnt-3 is present during development of the cerebellum and is restricted to the Purkinje cell layer in the adult. In motoneurons, Wnt-3 is a retrograde signal that controls terminal branching of muscle afferents. Human Wnt-3 is 98% homologous to mouse Wnt-3 protein and 84% homologous to human Wnt-3a protein. The human Wnt-3 gene clusters with the Wnt-15 gene at chromosome 17q21.31.



 
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