Product Datasheet  
TIMP-2 Antibody  
Catalog Number: 48343  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Goat
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P16035
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:1,000
    IHC: 1:50-500

    IP: 1-2 μg per 100-500 μg of total protein
  • other_names：  
  • CSC 21K antibody
    CSC-21K antibody
    CSC21K antibody
    Metalloproteinase inhibitor 2 antibody
    Metalloproteinase inhibitor 2 precursor antibody
    TIMP 2 antibody
    TIMP metallopeptidase inhibitor 2 antibody
    TIMP-2 antibody
    TI
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, IF, IHC
  • Background：  
  • TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases,gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase.TIMP-1 was found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.



 
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