Product Datasheet
Estrogen Receptor-α (Phospho-Ser102) Antibody
Catalog Number: 11801
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P03372;
NCBI Gene#: 2099;
NCBI Protein#: NP_000116.2.
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Peptide sequence around phosphorylation site of Serine102(L-N-S(p)-V-S) derived from Human Estrogen Receptor-α.
- other_names:
- ER; ESR; ESR1; ESTR; NR3A1
- Purification:
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Specificity:
- The antibody detects endogenous levels of Estrogen Receptor-α only when phosphorylated at serine 102.
- Background:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
Greene G.L., Science 231:1150-1154(1986).
Green S., Nature 320:134-139(1986).
Pink J.J., Nucleic Acids Res. 24:962-969(1996).
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