Product Datasheet  
Smad1(Phospho-Ser465) Antibody  
Catalog Number: 11321  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q15797
    NCBI Protein: NP_001003688.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of serine 465 (I-S-S-V-S(p)) derived from Human Smad1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 55kd
    Western blotting: 1:500~1:1000
  • other_names：  
  • Mad-related protein 1; SMAD 1; hSMAD1; Transforming growth factor-beta-signaling protein 1;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
  • Specificity：  
  • The antibody detects endogenous level of Smad1 only when phosphorylated at serine 465.
  • Applications：  
  • WB
  • Background：  
  • Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).

    Hiroaki Seto, et al. (2004) J Clin Invest. March 1; 113(5): 718



 
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