Product Datasheet  
SIK3 Antibody  
Catalog Number: 25394  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Chicken
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9Y2K2
    Gene ID:23387
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against an 18 amino acid peptide near the carboxy terminus of human SIK3.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • SIK family kinase 3, Salt-inducible kinase 3, Serine, threonine-protein kinase SIK3, Serine, threonine-protein kinase QSK, QSK, L19
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • At least three isoforms of SIK3 are known to exist; this antibody will detect two isoforms. SIK3 antibody is predicted to not cross-react with SIK1 and SIK2.
  • Applications：  
  • ELISA WB
  • Background：  
  • Salt-inducible kinase family (SIKs) proteins are thought to have a role in steroidogenesis, adipogenesis or regulation of tumor malignancy. Three members (SIK1, SIK2 and SIK3) in the SIK family have been identified thus far. Their kinase domain sequences are closely homologous to those of AMP-activated protein kinase (AMPK). SIK3 can be phosphorylated by a tumor-suppressor kinase LKB1. It is highly and preferentially expressed in ovarian tumors but not in adenomyosis and leiomyoma and may be a potential diagnostic marker for ovarian cancers.



 
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