Product Datasheet
PFKM Rabbit mAb
Catalog Number: 77904
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
- Immunogen:
- A synthesized peptide derived from human Fructose 6 Phosphate Kinase
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- ATP-PFK, GSD7, PFK-1, PFK1, PFKA, PFKX, PPP1R122
- Purification:
- Affinity purification
- Background:
- Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
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